RAxML-NG v. 1.0.2 released on 22.02.2021 by The Exelixis Lab.
Developed by: Alexey M. Kozlov and Alexandros Stamatakis.
Contributors: Diego Darriba, Tomas Flouri, Benoit Morel, Sarah Lutteropp, Ben Bettisworth.
Latest version: https://github.com/amkozlov/raxml-ng
Questions/problems/suggestions? Please visit: https://groups.google.com/forum/#!forum/raxml

System: Intel(R) Xeon(R) Gold 6140 CPU @ 2.30GHz, 36 cores, 251 GB RAM

RAxML-NG was called at 23-Jun-2021 12:53:43 as follows:

raxml-ng --msa /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/2_msa/Q15049_trimmed_msa.fasta --data-type AA --model LG4X --prefix /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049 --seed 2 --threads 6 --tree rand{20} pars{20}

Analysis options:
  run mode: ML tree search
  start tree(s): random (20)
  random seed: 2
  tip-inner: OFF
  pattern compression: ON
  per-rate scalers: OFF
  site repeats: ON
  fast spr radius: AUTO
  spr subtree cutoff: 1.000000
  branch lengths: proportional (ML estimate, algorithm: NR-FAST)
  SIMD kernels: AVX2
  parallelization: coarse-grained (auto), PTHREADS (6 threads), thread pinning: OFF

[00:00:00] Reading alignment from file: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/2_msa/Q15049_trimmed_msa.fasta
[00:00:00] Loaded alignment with 98 taxa and 378 sites

WARNING: Sequences tr_A0A1D5Q1N9_A0A1D5Q1N9_MACMU_9544 and tr_G7PG55_G7PG55_MACFA_9541 are exactly identical!
WARNING: Sequences tr_H0Z0G3_H0Z0G3_TAEGU_59729 and tr_A0A218UY26_A0A218UY26_9PASE_299123 are exactly identical!
WARNING: Sequences tr_A0A0D9QYG1_A0A0D9QYG1_CHLSB_60711 and tr_A0A2K5ZW08_A0A2K5ZW08_MANLE_9568 are exactly identical!
WARNING: Sequences tr_A0A2D0QQS6_A0A2D0QQS6_ICTPU_7998 and tr_A0A2D0QQX6_A0A2D0QQX6_ICTPU_7998 are exactly identical!
WARNING: Duplicate sequences found: 4

NOTE: Reduced alignment (with duplicates and gap-only sites/taxa removed) 
NOTE: was saved to: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049.raxml.reduced.phy

Alignment comprises 1 partitions and 373 patterns

Partition 0: noname
Model: LG4X+R4
Alignment sites / patterns: 378 / 373
Gaps: 5.32 %
Invariant sites: 16.14 %


NOTE: Binary MSA file already exists: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049.raxml.rba

Parallelization scheme autoconfig: 6 worker(s) x 1 thread(s)

Parallel reduction/worker buffer size: 1 KB  / 0 KB

[00:00:00] Generating 20 random starting tree(s) with 98 taxa
[00:00:00] Data distribution: max. partitions/sites/weight per thread: 1 / 373 / 29840
[00:00:00] Data distribution: max. searches per worker: 4

Starting ML tree search with 20 distinct starting trees

[00:00:00 -31995.551961] Initial branch length optimization
[00:00:00 -26482.262464] Model parameter optimization (eps = 10.000000)
[00:00:10 -26371.404165] AUTODETECT spr round 1 (radius: 5)
[00:00:15 -16808.333256] AUTODETECT spr round 2 (radius: 10)
[00:00:22 -13918.330925] AUTODETECT spr round 3 (radius: 15)
[00:00:29 -13675.339937] AUTODETECT spr round 4 (radius: 20)
[00:00:35 -13675.330972] SPR radius for FAST iterations: 15 (autodetect)
[00:00:35 -13675.330972] Model parameter optimization (eps = 3.000000)
[00:00:42 -13612.862524] FAST spr round 1 (radius: 15)
[00:00:49 -12885.818506] FAST spr round 2 (radius: 15)
[00:00:55 -12844.484197] FAST spr round 3 (radius: 15)
[00:00:58 -12842.842047] FAST spr round 4 (radius: 15)
[00:01:02 -12842.841901] Model parameter optimization (eps = 1.000000)
[00:01:05 -12840.636509] SLOW spr round 1 (radius: 5)
[00:01:17 -12835.214273] SLOW spr round 2 (radius: 5)
[00:01:27 -12835.212685] SLOW spr round 3 (radius: 10)
[00:01:35 -12835.212559] SLOW spr round 4 (radius: 15)
[00:01:47 -12835.212550] SLOW spr round 5 (radius: 20)
[00:01:58 -12835.212550] SLOW spr round 6 (radius: 25)
[00:02:02] [worker #1] ML tree search #2, logLikelihood: -12834.679765
[00:02:07] [worker #2] ML tree search #3, logLikelihood: -12832.134733
[00:02:07 -12835.212550] Model parameter optimization (eps = 0.100000)

[00:02:09] [worker #0] ML tree search #1, logLikelihood: -12835.172502

[00:02:09 -30560.443974] Initial branch length optimization
[00:02:09 -25977.075393] Model parameter optimization (eps = 10.000000)
[00:02:10] [worker #4] ML tree search #5, logLikelihood: -12834.638304
[00:02:12] [worker #5] ML tree search #6, logLikelihood: -12831.606325
[00:02:13] [worker #3] ML tree search #4, logLikelihood: -12834.679781
[00:02:18 -25885.827114] AUTODETECT spr round 1 (radius: 5)
[00:02:23 -17097.549616] AUTODETECT spr round 2 (radius: 10)
[00:02:31 -14057.762097] AUTODETECT spr round 3 (radius: 15)
[00:02:39 -13496.883783] AUTODETECT spr round 4 (radius: 20)
[00:02:46 -13496.882053] SPR radius for FAST iterations: 15 (autodetect)
[00:02:46 -13496.882053] Model parameter optimization (eps = 3.000000)
[00:02:51 -13461.724212] FAST spr round 1 (radius: 15)
[00:02:58 -12849.870146] FAST spr round 2 (radius: 15)
[00:03:03 -12842.697760] FAST spr round 3 (radius: 15)
[00:03:07 -12841.083813] FAST spr round 4 (radius: 15)
[00:03:11 -12841.083635] Model parameter optimization (eps = 1.000000)
[00:03:14 -12839.251734] SLOW spr round 1 (radius: 5)
[00:03:24 -12835.152228] SLOW spr round 2 (radius: 5)
[00:03:34 -12835.152219] SLOW spr round 3 (radius: 10)
[00:03:43 -12835.152219] SLOW spr round 4 (radius: 15)
[00:03:55 -12835.152219] SLOW spr round 5 (radius: 20)
[00:04:06 -12835.152219] SLOW spr round 6 (radius: 25)
[00:04:08] [worker #5] ML tree search #12, logLikelihood: -12833.277095
[00:04:14] [worker #2] ML tree search #9, logLikelihood: -12834.611850
[00:04:16 -12835.152219] Model parameter optimization (eps = 0.100000)

[00:04:17] [worker #0] ML tree search #7, logLikelihood: -12835.146598

[00:04:17 -32379.267591] Initial branch length optimization
[00:04:17 -27155.473875] Model parameter optimization (eps = 10.000000)
[00:04:25] [worker #3] ML tree search #10, logLikelihood: -12834.611846
[00:04:25 -27047.854371] AUTODETECT spr round 1 (radius: 5)
[00:04:29] [worker #1] ML tree search #8, logLikelihood: -12831.606312
[00:04:29] [worker #4] ML tree search #11, logLikelihood: -12834.611851
[00:04:30 -16566.595752] AUTODETECT spr round 2 (radius: 10)
[00:04:37 -13904.990223] AUTODETECT spr round 3 (radius: 15)
[00:04:45 -13469.830162] AUTODETECT spr round 4 (radius: 20)
[00:04:51 -13469.828979] SPR radius for FAST iterations: 15 (autodetect)
[00:04:51 -13469.828979] Model parameter optimization (eps = 3.000000)
[00:04:57 -13418.199719] FAST spr round 1 (radius: 15)
[00:05:05 -12856.807238] FAST spr round 2 (radius: 15)
[00:05:10 -12839.891359] FAST spr round 3 (radius: 15)
[00:05:14 -12839.700921] FAST spr round 4 (radius: 15)
[00:05:17 -12839.700918] Model parameter optimization (eps = 1.000000)
[00:05:20 -12837.421142] SLOW spr round 1 (radius: 5)
[00:05:32 -12831.661554] SLOW spr round 2 (radius: 5)
[00:05:41 -12831.661451] SLOW spr round 3 (radius: 10)
[00:05:50 -12831.661445] SLOW spr round 4 (radius: 15)
[00:06:02 -12831.661445] SLOW spr round 5 (radius: 20)
[00:06:13 -12831.661445] SLOW spr round 6 (radius: 25)
[00:06:22 -12831.661445] Model parameter optimization (eps = 0.100000)
[00:06:23] [worker #2] ML tree search #15, logLikelihood: -12832.173599

[00:06:24] [worker #0] ML tree search #13, logLikelihood: -12831.606327

[00:06:24 -32469.783643] Initial branch length optimization
[00:06:25 -27073.508440] Model parameter optimization (eps = 10.000000)
[00:06:25] [worker #1] ML tree search #14, logLikelihood: -12835.198849
[00:06:26] [worker #5] ML tree search #18, logLikelihood: -12834.679848
[00:06:31] [worker #3] ML tree search #16, logLikelihood: -12831.606242
[00:06:33 -26954.730797] AUTODETECT spr round 1 (radius: 5)
[00:06:37] [worker #4] ML tree search #17, logLikelihood: -12834.716909
[00:06:37 -18196.662571] AUTODETECT spr round 2 (radius: 10)
[00:06:45 -14143.553229] AUTODETECT spr round 3 (radius: 15)
[00:06:53 -13834.043579] AUTODETECT spr round 4 (radius: 20)
[00:07:01 -13834.033235] SPR radius for FAST iterations: 15 (autodetect)
[00:07:01 -13834.033235] Model parameter optimization (eps = 3.000000)
[00:07:06 -13774.792741] FAST spr round 1 (radius: 15)
[00:07:14 -12892.241026] FAST spr round 2 (radius: 15)
[00:07:21 -12835.589402] FAST spr round 3 (radius: 15)
[00:07:25 -12835.589259] Model parameter optimization (eps = 1.000000)
[00:07:27 -12835.121150] SLOW spr round 1 (radius: 5)
[00:07:37 -12834.188198] SLOW spr round 2 (radius: 5)
[00:07:47 -12834.188091] SLOW spr round 3 (radius: 10)
[00:07:56 -12834.188090] SLOW spr round 4 (radius: 15)
[00:08:08 -12834.188090] SLOW spr round 5 (radius: 20)
[00:08:19 -12834.188090] SLOW spr round 6 (radius: 25)
[00:08:27 -12834.188090] Model parameter optimization (eps = 0.100000)

[00:08:29] [worker #0] ML tree search #19, logLikelihood: -12834.149307

[00:08:46] [worker #1] ML tree search #20, logLikelihood: -12834.611810

Optimized model parameters:

   Partition 0: noname
   Rate heterogeneity: FREE (4 cats, mean),  weights&rates: (0.362279,0.391108) (0.238534,0.562908) (0.245782,1.162141) (0.153404,2.857830) 
   Base frequencies (model): 
M0: 0.147383 0.017579 0.058208 0.017707 0.026331 0.041582 0.017494 0.027859 0.011849 0.076971 0.147823 0.019535 0.037132 0.029940 0.008059 0.088179 0.089653 0.006477 0.032308 0.097931 
M1: 0.063139 0.066357 0.011586 0.066571 0.010800 0.009276 0.053984 0.146986 0.034214 0.088822 0.098196 0.032390 0.021263 0.072697 0.016761 0.020711 0.020797 0.025463 0.045615 0.094372 
M2: 0.062457 0.066826 0.049332 0.065270 0.006513 0.041231 0.058965 0.080852 0.028024 0.037024 0.075925 0.064131 0.019620 0.028710 0.104579 0.056388 0.062027 0.008241 0.033124 0.050760 
M3: 0.106471 0.074171 0.044513 0.096390 0.002148 0.066733 0.158908 0.037625 0.020691 0.014608 0.028797 0.105352 0.007864 0.007477 0.083595 0.055726 0.047711 0.003975 0.010088 0.027159 
   Substitution rates (model): 
M 0: 0.295719 0.067388 0.253712 1.029289 0.107964 0.514644 10.868848 0.380498 0.084223 0.086976 0.188789 0.286389 0.155567 1.671061 2.132922 0.529591 0.115551 0.102453 0.916683 0.448317 0.457483 0.576016 1.741924 0.736017 0.704334 5.658311 0.123387 0.221777 93.433377 0.382175 0.235965 6.535048 0.525521 0.303537 0.641259 0.289466 0.102065 2.358429 0.251987 0.216561 0.503084 0.435271 4.873453 0.090748 0.033310 0.746537 0.128905 0.127321 0.904011 0.939733 0.435450 0.046646 0.262076 0.043986 0.189008 0.599450 109.901504 1.070052 5.229858 0.052764 0.021407 0.621146 0.081091 0.205164 5.164456 0.747330 0.308078 0.260889 0.185083 0.080708 0.029955 0.084794 1.862626 0.553477 0.151733 0.230320 0.096955 0.352526 0.590018 0.386853 1.559564 0.606648 0.587531 0.592318 0.885230 4.117654 0.246260 6.508329 0.054187 0.195703 1.669092 0.810168 0.066081 2.437439 0.165666 0.106333 0.093417 0.035149 0.072549 1.202023 1.634845 0.060194 0.069359 2.448827 0.232297 0.064822 3.537387 0.435384 0.290413 0.280695 0.105999 0.206603 0.404968 0.048984 0.069963 0.256662 0.228519 0.241077 4.320442 3.656545 0.290216 0.307466 0.096556 0.306067 0.204296 0.504221 1.991533 0.655465 6.799829 11.291065 0.961142 0.448965 6.227274 20.304886 0.205944 1.495537 0.091940 1.994320 0.754940 0.170343 0.050315 0.372166 0.206332 0.097050 5.381403 0.122332 3.256485 2.261319 0.848067 0.064441 0.102493 0.459041 0.133091 0.561215 0.457430 0.163849 5.260446 0.360946 0.389413 0.033291 0.115301 0.112593 1.559944 0.426508 0.132547 0.498634 0.559069 0.264728 0.693307 0.438856 0.306683 0.109129 18.392863 66.647302 0.400021 4.586081 2.099355 0.411347 0.476350 0.584622 3.634276 0.101797 0.148995 0.089177 0.034710 0.063603 0.755865 20.561407 0.133790 0.154902 
M 1: 0.066142 0.590377 0.069930 9.850951 1.101363 0.150375 0.568586 0.051668 0.127170 0.292429 0.071458 1.218562 0.075144 7.169085 30.139501 13.461692 0.021372 0.045779 4.270235 0.468325 0.013688 0.302287 1.353957 0.028386 0.037750 0.262130 0.016923 0.064289 0.855973 0.079621 0.011169 0.161937 0.276530 0.161053 0.081472 0.036742 0.030342 2.851667 3.932151 8.159169 0.219934 0.421974 2.468752 0.344765 0.210724 1.172204 0.763553 0.082464 0.726566 11.149790 4.782635 0.058046 0.498072 0.258487 0.146882 0.249672 0.560142 0.046719 0.106259 0.003656 0.004200 0.014189 0.009876 0.002656 0.040244 0.267322 0.053740 0.006597 0.027639 0.012745 0.582670 0.005035 0.275844 0.098208 0.445038 1.217010 0.033969 1.988516 0.681161 0.825960 18.762977 11.949233 0.286794 0.534219 4.336817 3.054085 0.129551 4.210126 0.165753 1.088704 1.889645 3.344809 0.111063 2.067758 3.547017 2.466507 0.188236 0.203493 0.281953 0.037250 0.029788 0.008541 0.014768 0.125869 0.056702 0.004186 0.110993 0.201148 0.139705 0.009201 0.012095 0.043812 0.013513 0.002533 0.005848 0.031390 0.021612 0.004854 0.129497 0.976631 0.053397 0.019475 0.004964 0.015539 0.031779 0.064558 0.065585 0.079927 0.095591 0.196886 0.408834 0.126088 0.037226 0.452302 0.016212 7.278994 0.029917 7.918203 0.450964 0.169797 0.104288 1.578530 0.015909 0.094365 16.179952 0.042762 14.799537 1.506485 0.637893 0.123793 0.641351 0.154810 0.140750 3.416059 0.259400 0.009457 0.090576 0.292108 0.297913 0.017172 0.021976 0.032578 1.375871 0.457399 0.598048 4.418398 0.239749 0.168432 2.950318 0.143327 0.328689 0.125011 0.562720 1.414883 0.227807 3.478333 2.984862 0.061299 0.077470 1.050562 13.974326 0.154326 0.224675 0.112000 0.060703 0.123480 5.294490 0.447011 0.033381 0.045528 
M 2: 0.733336 0.558955 0.503360 4.149599 1.415369 1.367574 1.263002 0.994098 0.517204 0.775054 0.763094 1.890137 0.540460 0.200122 4.972745 1.825593 0.450842 0.526135 3.839269 0.597671 0.058964 2.863355 2.872594 0.258365 0.366868 2.578946 0.358350 0.672023 5.349861 0.691594 0.063347 0.032875 0.821562 0.580847 0.661866 0.265730 0.395134 5.581680 1.279881 1.335650 0.397108 1.840061 5.739035 0.284730 0.109781 1.612642 0.466979 0.141582 0.019509 4.670980 1.967383 0.088064 0.581928 0.145401 0.225860 0.434096 2.292917 1.024707 0.821921 0.027824 0.021443 0.088850 0.060820 0.018288 0.042687 1.199607 0.420710 0.037642 0.141233 0.090101 1.043232 0.209978 0.823594 3.039380 1.463390 1.983693 0.397640 2.831098 4.102068 0.059723 5.901348 2.034980 2.600668 5.413080 4.193725 4.534772 0.377181 4.877840 0.370939 1.298542 3.509873 2.646440 0.087872 0.072299 1.139018 0.864479 0.390688 0.322761 0.625409 0.496780 0.532488 0.232460 0.169219 0.755219 0.379926 0.020447 0.023282 0.503875 0.577513 0.109318 0.153776 0.696533 0.398817 0.008940 0.043707 0.436013 0.087640 0.064863 0.036426 1.673207 0.124068 0.218118 0.039217 0.104335 0.349195 0.838324 0.888693 0.488389 1.385133 0.050226 0.962470 0.502294 1.065585 8.351808 0.377304 5.102837 0.561690 7.010411 3.054968 0.039318 0.204155 2.653232 0.564368 0.854294 15.559906 0.401070 8.929538 5.525874 0.067505 0.273372 0.437116 1.927515 0.940458 2.508169 1.357738 0.043394 0.023126 0.567639 1.048288 0.120994 0.180650 0.449074 3.135353 0.012695 0.570771 2.319555 1.856122 0.975427 3.404087 0.015631 0.458799 0.151684 4.154750 11.429924 1.457957 0.233109 0.077004 0.011074 0.026268 0.052132 8.113282 0.377578 0.429221 0.260296 0.222293 0.273138 2.903836 4.731579 0.564762 0.681215 
M 3: 0.658412 0.566269 0.854111 0.884454 1.309554 1.272639 1.874713 0.552007 0.227683 0.581512 0.695190 0.967985 0.344015 0.978992 3.427163 2.333253 0.154701 0.221089 2.088785 0.540749 0.058015 5.851132 2.294145 0.182966 0.684164 3.192521 0.528161 1.128882 3.010922 1.012866 0.227296 0.156635 0.878405 0.802754 0.830884 0.431617 0.456530 3.060574 1.279257 1.438430 0.431464 2.075952 4.840271 0.644656 0.266076 2.084975 0.720060 0.291854 0.028961 4.071574 2.258357 0.073037 1.238426 0.199728 0.160296 0.482619 2.992763 1.296206 0.841829 0.031467 0.048542 0.132774 0.133055 0.056045 0.209188 0.925172 0.360522 0.094591 0.313945 0.118104 0.992259 0.086318 2.149634 5.103188 3.775817 3.954021 0.190734 1.776095 4.495841 0.264277 7.063879 2.221150 3.017954 8.558815 4.310199 2.130054 0.571406 4.137385 0.437589 2.071689 2.498630 1.763546 0.116381 0.296578 1.033710 1.283423 0.312579 0.305772 0.681277 0.507160 0.351381 0.189152 0.217780 0.767361 0.278392 0.092075 0.177263 0.451893 0.653836 0.074620 0.181992 0.752277 0.679853 0.025780 0.082005 0.326441 0.343977 0.195877 0.217424 3.057583 0.377558 0.401252 0.072258 0.241015 0.665865 1.266791 0.680174 0.717301 4.001286 0.362942 1.189259 0.964545 1.350568 12.869737 0.531100 8.904999 0.652629 10.091413 2.671718 0.086367 0.359932 4.797423 0.336801 1.021885 23.029406 0.440178 14.013035 5.069337 0.539010 0.742569 0.780580 1.331875 1.531589 4.414850 1.082703 0.091278 0.172734 0.693405 1.422571 0.068958 0.163829 0.481711 4.643214 0.121821 0.584083 4.216178 1.677263 1.575754 5.046403 0.161015 1.531223 0.599244 5.832025 33.873091 1.914768 1.287474 0.444362 0.076328 0.079916 0.466823 5.231362 0.548763 0.831890 0.382271 0.208791 0.307846 3.717971 5.910440 0.282540 0.964421 


Final LogLikelihood: -12831.606242

AIC score: 26061.212484 / AICc score: 26508.403495 / BIC score: 26844.256429
Free parameters (model + branch lengths): 199

WARNING: Best ML tree contains 9 near-zero branches!

Best ML tree with collapsed near-zero branches saved to: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049.raxml.bestTreeCollapsed
Best ML tree saved to: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049.raxml.bestTree
All ML trees saved to: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049.raxml.mlTrees
Optimized model saved to: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049.raxml.bestModel

Execution log saved to: /cta/users/eakkoyun/WORKFOLDER/PROD/run_040621/phylogeny-snakemake/results/Q15049/3_mltree/Q15049.raxml.log

Analysis started: 23-Jun-2021 12:53:43 / finished: 23-Jun-2021 13:02:29

Elapsed time: 526.161 seconds